pretiox titanium dioxide manufacturers

In addition to its innovative products, O2Ti also places a strong emphasis on customer service. The company has a dedicated team of engineers and technicians who provide round-the-clock support to ensure that its customers' systems are up and running smoothly The company has a dedicated team of engineers and technicians who provide round-the-clock support to ensure that its customers' systems are up and running smoothly The company has a dedicated team of engineers and technicians who provide round-the-clock support to ensure that its customers' systems are up and running smoothly The company has a dedicated team of engineers and technicians who provide round-the-clock support to ensure that its customers' systems are up and running smoothlychina o2ti. This level of support has helped O2Ti build a strong reputation for reliability and trustworthiness in the industry.

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We are a titanium dioxide manufacturer from China, our company has a perfect production capacity supporting, the main business is CR-930 series, anatase titanium dioxide BA01-01, CA100 series, Litho series, products with strong thickness resistance, good dispersion, high coverage. Widely used in paint, paper, rubber, coatings, tires, ceramics and other industries. Welcome your communication, negotiation and cooperation.
The company's main CR-930 series, Anatase titanium dioxide BA01-01, CA100 series, Lide powder series, has a professional management team, advanced production equipment and excellent technical advantages. The quality of our products is guaranteed and can also meet the manufacturing needs of different customers.
The factory is different from the dealer, we only provide FOB price of Tianjin port for the time being, we do not support CIF price for the time being, please understand. If necessary, the factory will provide you with quotation.
I'm Mia from Hebei Caiqing New Material Technology Co., LTD. My telephone number is +86 15694839000. My email address is sales02@cqtitaniumdioxide.com. We look forward to establishing long-term cooperative relations with your company.

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Different dermal cell types have been reported to differ in their sensitivity to nano-sized TiO2 . Kiss et al. exposed human keratinocytes (HaCaT), human dermal fibroblast cells, sebaceous gland cells (SZ95) and primary human melanocytes to 9 nm-sized TiO2 particles at concentrations from 0.15 to 15 μg/cm2 for up to 4 days. The particles were detected in the cytoplasm and perinuclear region in fibroblasts and melanocytes, but not in kerati-nocytes or sebaceous cells. The uptake was associated with an increase in the intracellular Ca2+ concentration. A dose- and time-dependent decrease in cell proliferation was evident in all cell types, whereas in fibroblasts an increase in cell death via apoptosis has also been observed. Anatase TiO2 in 20–100 nm-sized form has been shown to be cytotoxic in mouse L929 fibroblasts. The decrease in cell viability was associated with an increase in the production of ROS and the depletion of glutathione. The particles were internalized and detected within lysosomes. In human keratinocytes exposed for 24 h to non-illuminated, 7 nm-sized anatase TiO2, a cluster analysis of the gene expression revealed that genes involved in the “inflammatory response” and “cell adhesion”, but not those involved in “oxidative stress” and “apoptosis”, were up-regulated. The results suggest that non-illuminated TiO2 particles have no significant impact on ROS-associated oxidative damage, but affect the cell-matrix adhesion in keratinocytes in extracellular matrix remodelling. In human keratinocytes, Kocbek et al. investigated the adverse effects of 25 nm-sized anatase TiO2 (5 and 10 μg/ml) after 3 months of exposure and found no changes in the cell growth and morphology, mitochondrial function and cell cycle distribution. The only change was a larger number of nanotubular intracellular connections in TiO2-exposed cells compared to non-exposed cells. Although the authors proposed that this change may indicate a cellular transformation, the significance of this finding is not clear. On the other hand, Dunford et al. studied the genotoxicity of UV-irradiated TiO2 extracted from sunscreen lotions, and reported severe damage to plasmid and nuclear DNA in human fibroblasts. Manitol (antioxidant) prevented DNA damage, implying that the genotoxicity was mediated by ROS.

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