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Titanium dioxide (TiO2) is by far the most suited white pigment to obtain whiteness and hiding power in coatings, inks and plastics. This is because it has an extremely high refractive index and it does not absorb visible light. TiO2 is also readily available as particles with the right size (d ≈ 280 nm) and the right shape (more or less spherical) as well as with a variety of post-treatments.

However, the pigment is expensive, especially when the volume prices of systems are used. And, there always remains a need to develop a full-proof strategy to obtain the best results in terms of cost/performance ratio, scattering efficiency, dispersion… while using it in coating formulations. Are you searching for the same?

Explore the detailed knowledge of TiO2 pigment, its scattering efficiency, optimization, selection, etc. to achieve the best possible white color strength and hiding power in your formulations.

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lithopone suppliers2025-08-16 03:10
1750

In an early study Jani et al. administred rutile TiO2 (500 nm) as a 0.1 ml of 2.5 % w/v suspension (12.5 mg/kg BW) to female Sprague Dawley rats, by oral gavage daily for 10 days and detected presence of particles in all the major gut associated lymphoid tissue as well as in distant organs such as the liver, spleen, lung and peritoneal tissue, but not in heart and kidney. The distribution and toxicity of nano- (25 nm, 80 nm) and submicron-sized (155 nm) TiO2 particles were evaluated in mice administered a large, single, oral dosing (5 g/kg BW) by gavage. In the animals that were sacrificed two weeks later, ICP-MS analysis showed that the particles were retained mainly in liver, spleen, kidney, and lung tissues, indicating that they can be transported to other tissues and organs after uptake by the gastrointestinal tract. Interestingly, although an extremely high dose was administrated, no acute toxicity was observed. In groups exposed to 80 nm and 155 nm particles, histopathological changes were observed in the liver, kidney and in the brain. The biochemical serum parameters also indicated liver, kidney and cardiovascular damage and were higher in mice treated with nano-sized (25 or 80 nm) TiO2 compared to submicron-sized (155 nm) TiO2. However, the main weaknesses of this study are the use of extremely high single dose and insufficient characterisation of the particles.

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lithopone suppliers2025-08-16 02:37
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