tr 93 titanium dioxide supplier

In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

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The prices of lithopone are influenced by several factors, including raw material costs, production capacity, supply and demand dynamics, regional economic conditions, and environmental regulations. Zinc and sulfur, the primary components of lithopone, are subject to fluctuations in their global market prices, which directly impacts the cost of lithopone production. Additionally, stricter environmental norms often lead to increased production costs for manufacturers, affecting the final pricing.

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