The price trendss for titanium dioxide kept on the lower side of the scale during the first half of 2023. As the paint and coatings industries reduced their offtakes,  the abundant supply of the product in the market led to a fall in prices. The prices also suffered from falling energy costs and declining freight charges. Further, the rising speculations of a global recession caused manufacturers to participate actively in destocking.

Animal studies have shown that, when consumed as a food additive, titanium dioxide can induce intestinal inflammation.

TiO₂ comes in many different forms. However, only a few of these forms are considered food-grade (acceptable to be added to food). Many studies that raised concern about the safety of TiO₂, including the concern for genotoxicity, used forms of TiO₂ that are not considered acceptable for use in food and have different properties than food-grade TiO₂. Other studies did use food-grade TiO₂, but took steps to break the material down into smaller particles than what would normally be found in food.