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A few non-dietary studies have reported adverse effects in the gastrointestinal tract of laboratory animals given food-grade TiO2. However, these same effects were not seen when the same or higher doses of food-grade TiO2 were administered in the animals' diet. Dietary studies best reflect how humans are exposed to TiO2 from food. Thus, the Food Directorate placed the most emphasis on the results of these studies in the state of the science report.

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In conclusion, the gravimetric analysis factory is a critical component of the titanium dioxide industry. Its accurate measurement techniques ensure the quality and consistency of titanium dioxide products, while also driving innovation and research in the field. With the demand for titanium dioxide products on the rise, the role of the gravimetric analysis factory will continue to be pivotal in meeting industry standards and consumer expectations.

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  • While the conclusions of the EU expert panel were considered in this report, Health Canada's Food Directorate conducted its own comprehensive review of the available science. This included evaluating new scientific data that addressed some of the uncertainties identified by the EU expert panel and were not available at the time of their review.