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In a 2020 study published in the Journal of Trace Elements in Medicine and Biology, researchers conducted an in vitro experiment to analyze the effects of TiO2 nanoparticles on a human neuroblastoma (SH-SY5Y) cell line. The scientists evaluated “reactive oxygen species (ROS) generation, apoptosis, cellular antioxidant response, endoplasmic reticulum stress and autophagy.” The results showed that exposure to the nanoparticles “induced ROS generation in a dose dependent manner, with values reaching up to 10 fold those of controls. Nrf2 nuclear localization and autophagy also increased in a dose dependent manner. Apoptosis increased by 4- to 10-fold compared to the control group, depending on the dose employed.” 

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In conclusion, the art of lithopone quotes is more than just an aesthetic choice; it is a cultural phenomenon that encapsulates the spirit of Chinese wisdom and artistic innovation. By marrying profound quotes with visually striking designs, these prints offer a glimpse into the intellectual and creative life of China. They serve as a bridge between the ancient and the modern, the local and the global, inviting all to partake in the rich tapestry of Chinese thought and artistry.

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