titanium dioxide paste

titanium oxide and 2 per cent' sulphuric acidand 63 per cent water, are slowly added to a solution containing 1050 pounds of barium sulphide, held in a large cylindrical tank, provided with a rotary agitation :capable of producing rapid agitation. The mass isthus v rapidly agitated, and the 2 per cent of sulphuric acid contained in the titanium acid cake reacts with a small portion of the barium sulphide. This reaction may be represented by the following equation TiO H 80 The free sulphuric acid of the titanium acid cake is neutralized by thebarium sul-' phide solution, forming barium sulphate and hydrogen sulphide, as indicated by the above equation. As the sulphuric acid is present only in a small percentage, the major porltiion of the barium sulphide remains as suc very fine colloidal suspension. The barium sulphate produced is also very fine, and the presence of this. very fine barium sulphate in suspension, and also of the very fine colloidal titanium oxide, is believed to be the explanation of the great improvement in the properties of the finished lithopone.

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At the present JECFA meeting, the committee considered additional toxicological studies relevant to the safety assessment of the chemical that investigated its toxicokinetics, acute toxicity, short-term toxicity, long-term toxicity and carcinogenicity, genotoxicity, and reproductive and developmental toxicity, as well as special studies addressing its short-term initiation/promotion potential for colon cancer. The experts acknowledged that a large number of toxicological studies have been conducted using test materials, including nanoparticles, having size distributions and physico-chemical properties not comparable to real-world uses of titanium dioxide as a food additive. The studies on non-representative materials were evaluated by JECFA, but the committee concluded that such studies are not relevant to the safety assessment of the additive.

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