Inhaling high concentrations of titanium dioxide dust or fumes, which may occur in occupational settings — such as in the production or processing of products containing the mineral — may cause respiratory problems like coughing, wheezing and shortness of breath, in addition to eye and skin irritation.

In addition to Skittles, other candies that contain titanium dioxide include Nice! mints, Trolli sour gummies and Ring Pops, according to Environmental Working Group.