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Leading TiO2 producers include companies such as Chemours, Tronox, Cristal Global, Venator Materials PLC (formerly known as Huntsman), and Kronos Worldwide. These corporations often have multiple production sites around the globe, ensuring a steady supply chain for this critical material These corporations often have multiple production sites around the globe, ensuring a steady supply chain for this critical material These corporations often have multiple production sites around the globe, ensuring a steady supply chain for this critical material These corporations often have multiple production sites around the globe, ensuring a steady supply chain for this critical materialhitox tio2 manufacturers. They invest heavily in research and development to create more efficient production processes and higher quality TiO2 products.

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JECFA previously assessed titanium dioxide at its 13th meeting, at which time the expert committee assigned a “not specified” ADI for the additive due to an absence of significant absorption and a lack of toxicological effects in the available experimental animal and human studies. Since its original evaluation by JECFA, titanium dioxide has become a public point of contention, with its ban being introduced (and then subsequently withdrawn) in California legislation in 2023, a legal battle playing out in the EU over the additive’s ban and classification as a carcinogen in 2022, and the European Food Safety Authority (EFSA) calling titanium dioxide unsafe. However, supporters of titanium dioxide say that claims about its dangers are founded in unreliable studies, and some recent research has supported its safety as a food additive.

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