Duan et al. administered 125 mg/kg BW or 250 mg/kg BW of anatase TiO₂ (5 nm) intragastrically to mice continuously for 30 days. The exposed mice lost body weight, whereas the relative liver, kidney, spleen and thymus weights increased. Particles seriously affected the haemostasis of the blood and the immune system. The decrease in the immune response could be the result of damage to the spleen, which is the largest immune organ in animals and plays an important role in the immune response. Powel et al. demonstrated that TiO₂ NPs may trigger immune reactions of the intestine after oral intake. They showed that TiO₂ NPs conjugated with bacterial lipopolysaccharide, but not TiO₂ NPs or lipopolysaccharide alone, trigger the immune response in human peripheral blood mononuclear cells and in isolated intestinal tissue. This indicates that TiO₂ NPs may be important mediators in overcoming normal gut-cell hyporesponsiveness to endogenous luminal molecules, which may be particularly relevant to patients with inflammatory bowel disease, which is characterized by an abnormal intestinal permeability.

In addition to the toxic effects of TiO₂ NPs, discussed in previous chapters, these NPs have been also shown to promote photosynthesis and nitrogen metabolism, resulting in the enhanced growth of spinach. It increases the absorption of light and accelerates the transfer and transformation of the light energy. It was also found that treatment with nano-sized TiO₂ significantly increased the level of antioxidant enzymes, and decreased the ROS accumulation and malonyldialdehyde content in spinach chloroplasts under visible and UV irradiation. TiO₂ NPs also increased the superoxide dismutase activity of germinating soybean, enhanced its antioxidant ability, and promoted seed germination and seedling growth.

The natural barite containing more than 95% of barium sulfate is mixed with anthracite in a ratio of 3:1 (mass), and is pulverized to a diameter of about 2 cm or less to enter a reduction furnace, and the front stage of the furnace temperature is controlled by 1000 to 1200 ° C, and the latter stage is 500 to 600 ° C, the reduction furnace rotates at a speed of 80s per revolution, the reaction conversion rate is 80% to 90%, the obtained barium sulfide enters the leaching device, the control temperature is above 65 ° C, and the content of barium sulfide is 701%, and then enters the clarification. The barrel is clarified and then added with zinc sulfate to control the zinc sulfate content to be greater than 28%, and the pH is 8-9, and a mixture of barium sulfate and zinc sulfide having a density of

There are many uses of titanium dioxide that we don't know about because they were made exempt from being on the package in 1977, said Faber, who added that nothing much has changed since – other than the FDA approving some other uses of the color additive, such as expanding the use of mica-based pearlescent pigments (prepared from titanium dioxide) as color additives in distilled spirits over recent years.