Because of its unique pigment and fine-milled texture, titanium dioxide has become popular over the past century in a wide variety of different products. These include adhesives, paints, plastics, rubbers, textiles, inks, ceramics, and even some pharmaceuticals, foods, and hygiene products.
UV–vis spectra were carried out in the supernatant of both vitamins@P25TiO2NPs samples after centrifugation to measure the amount of unbound vitamin. Standard curves at 375 nm and 255 nm were done for vitamin B2 and C, respectively, using a Synergy BioTeK multi-mode microplate reader.
The US and Canada, however, approve the use of titanium dioxide as a food additive. Canada's recent review of titanium dioxide reconfirmed its safety and pointed out that many of the toxicity studies the EU reviewed were not relevant to the safety of titanium dioxide as a food ingredient, and that the ban is based on an abundance of caution and uncertainty.
After oral ingestion, the absorption of titanium dioxide particles is low, however they can accumulate in the body, Maged Younes, chair of the European Food Safety Authority's expert Panel on Food Additives and Flavourings, said in a May 2021 statement.