rutile and anatase factory

The global lithopone market has seen a steady growth over the years, driven by the increasing demand from end-use industries, particularly construction and coatings. However, the market faces challenges, including price volatility due to raw material fluctuations and the ongoing shift towards more eco-friendly alternatives. This has led suppliers to invest in research and development to improve the sustainability of their products and processes.

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In a review published in 2022 in the journal Archives of Toxicologyresearchers found that the ingestion of E171 is a “a definite health risk for consumers and their progeny.” After reviewing dozens of in vivoex vivo and in vitro studies on the toxicity of E171, the researchers wrote that two facts must be noted: “First, reprotoxicity studies show that animals of both sexes are impacted by the toxicity of these nanoparticles, underlining the importance of conducting in vivo studies using both male and female animals. Second, human exposure begins in utero via maternal-fetal transfer and continues after birth by breastfeeding. Children are then chronically re-exposed due to their food preferences. To be relevant to the human in vivo situation, experimental studies should therefore consider nanoparticle exposure with respect to the age or life period of the studied population.”

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