77891 titanium dioxide manufacturer

A study published in the Journal of Agricultural and Food Chemistry in 2019 sought to examine the effects of titanium dioxide on intestinal inflammation. Researchers did this by feeding rats titanium dioxide nanoparticles and found that, after the course of two to three months, the animals had lower body weights and induced intestinal inflammation. The researchers also found the nanoparticles altered gut microbiota composition and aggravated chronic colitis. The rats also experienced reduced populations of CD4+T cells (which are cells that help organize immune responses by prompting other immune cells to fight infection), regulatory T cells, and white blood cells in mesenteric lymph nodes. The researchers wrote: “Dietary TiO2 nanoparticles could interfere with the balance of the immune system and dynamic of gut microbiome, which may result in low-grade intestinal inflammation and aggravated immunological response to external stimulus, thus introducing potential health risk.”

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To address these challenges, researchers are exploring alternative production methods that are more energy-efficient and environmentally friendly. For example, the use of solar energy to power the oxidation of titanium ore has been proposed as a way to reduce the energy consumption of the sulfate process. Other approaches include the development of new catalysts that can replace sulfuric acid in the oxidation step, as well as the exploration of bio-based feedstocks for TiO2 production.

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