Panzhihua Dongfang TiO2 manufacturer has 28 patents related to titanium dioxide production by sulfuric acid method, 3 research results, and 5 registered trademarks. Excellent quality, excellent covering power, excellent system dispersion, good whiteness, high brightness, and low oil absorption. The company’s products are exported to more than 40 countries and regions in the world, and the export ratio is nearly 40%. It is the second largest exporter in Panzhihua City after Panzhihua Iron and Steel. Top 50, Sichuan Enterprise Technology Center, Panzhihua Municipal Government “Advanced Foreign Trade Export Enterprise” and other titles

In a 2019 study published in the journal Nanotoxicology, researchers recreated the first phase of digestion in mice and fed them titanium dioxide, then examined whether accumulation occurred in the organs. Researchers wrote: “Significant accumulation of titanium was observed in the liver and intestine of E171-fed mice; in the latter a threefold increase in the number of TiO2 particles was also measured. Titanium accumulation in the liver was associated with necroinflammatory foci containing tissue monocytes/macrophages. Three days after the last dose, increased superoxide production and inflammation were observed in the stomach and intestine. Overall, [this] indicates that the risk for human health associated with dietary exposure to E171 needs to be carefully considered.”

Fig. 4. Hemolysis (%) values of samples, A: 0.2 mg/mL P25TiO₂NPs; B: 0.02 mg/mL P25TiO₂NPs; C: 0.2 mg/mL VitaminB2@P25TiO₂NPs; D: 0.02 mg/mL VitaminB2@P25TiO₂NPs after 3 h of irradiation (red) and 6 h (blue). SD <5 for all samples and p <0.05 between C-D and A-B.