titania tio2 factories

The conventional surface treatment methods of titanium alloy include glow discharge plasma deposition, oxygen ion implantation, hydrogen peroxide treatment, thermal oxidation, sol-gel method, anodic oxidation, microarc oxidation, laser alloying, and pulsed laser deposition. These methods have different characteristics and are applied in different fields. Glow discharge plasma deposition can get a clean surface, and the thickness of the oxide film obtained is 2 nm to 150 nm [28]. The oxide film obtained from oxygen ion implantation is thicker, about several microns [914]. Hydrogen peroxide treatment of titanium alloy surface is a process of chemical dissolution and oxidation [1516]. The dense part of the oxide film is less than 5 nm [1721]. The oxide film generated from the thermal oxidation method has a porous structure, and its thickness is commonly about 10-20 μm [2225]. The oxide film from the sol-gel method is rich in Ti-OH, a composition that could induce apatite nucleation and improve the combining of implants and bone. It has a thickness of less than 10 μm [2628]. Applied with the anodic oxidation method, the surface can generate a porous oxide film of 10 μm to 20 μm thickness [2931]. Similarly, the oxide film generated from the microarc oxidation method is also porous and has a thickness of 10 μm to 20 μm [3233].

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  • In general, nanoparticles have been shown to accumulate in the body, particularly in organs in the gastrointestinal tract, along with the liver, spleen, and capillaries of the lungs.

  • The National Cancer Institute tested TiO2 for possible carcinogenicity by the oral route of exposure by feeding rats and mice with TiO2 (size not specified) at doses 25,000 or 50,000 ppm TiO2 for 103 weeks. They concluded that TiO2 was not carcinogenic.Also, the study with rats fed diets containing up to 5 % TiO2 coated mica for 130 weeks showed no treatment-related carcinogenicity. Since the size and other TiO2 properties were not specified or determined, we cannot generalize this conclusion and we have to take into account other possible outcomes of this scenario in different exposure conditions (other size/crystalline structure of TiO2 etc.).