lithopone pigment supplier

In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

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The global market for 30-50nm TiO2 powders is witnessing a rapid expansion, driven by the increasing demand for eco-friendly and energy-efficient solutions. As a result, manufacturers are constantly exploring new ways to optimize production, enhance functionality, and cater to diverse industry requirements. From tailor-made formulations for specific applications to exploring the potential of TiO2 nanoparticles in next-generation technologies, these manufacturers are at the forefront of shaping the future of nanomaterials.

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