Binders hold the pigment particles together, solvents help in the application and drying process, and additives enhance properties like flow, adhesion, and durability Binders hold the pigment particles together, solvents help in the application and drying process, and additives enhance properties like flow, adhesion, and durabilitypaint pigment factory. The mixing is a delicate balance, as each component influences the final performance and appearance of the paint.In a study published in the journal Food and Chemical Toxicology in 2016, researchers investigated whether titanium dioxide exposure led to an increase in colorectal tumor creation in mice by using a colitis associated cancer model. By measuring tumor progression markers, the researchers found that mice given titanium dioxide experienced enhanced tumor formation in the distal colon. There was also a decrease of cells that act as a protective barrier in the colon. The researchers wrote: “These results suggest that E171 could worsen pre-existent intestinal diseases.”