In terms of manufacturers, there are many companies that produce calcium carbonate and titanium dioxide. Some of the top manufacturers of calcium carbonate include Omya, Imerys, and Minerals Technologies. These companies have large mining operations and production facilities in regions where calcium carbonate is abundant.

Titanium dioxide, or TiO2, sometimes referred to as E171, is an inorganic, solid substance used in a wide range of consumer goods including cosmetics, paint, plastic and food, according to the American Chemistry Council.

Titanium dioxide, a naturally occurring oxide of titanium, is widely recognized for its exceptional properties and versatility in various industries. Among its numerous applications, the production of tires stands out as a crucial area where titanium dioxide plays an indispensable role. This article aims to explore the significance of wholesale titanium dioxide in the tire manufacturing sector, emphasizing its properties, benefits, and the overall impact on product quality.

A significant body of research, mostly from rodent models and in vitro studies, has linked titanium dioxide with health risks related to the gut, including intestinal inflammation, alterations to the gut microbiota, and more. It is classified by the International Agency for Research on Cancer (IARC) in Group 2B, as possibly carcinogenic to humans.