The FDA first approved the use of titanium dioxide in food in 1966, following its 1960 removal (along with the removal of other color additives) from the agency's original Generally Recognized as Safe list. In 1977, titanium dioxide joined the list of color additives that are exempt from certification, which means titanium dioxide doesn't have to be listed on the packaging of every product it's used in, Faber noted.

1. Pigment and Food Coloring

Most commonly used in candy, it can also be found in salad dressings, chewing gum, ice cream, frozen pizzas, drink and jello mixes and many other food categories. Titanium dioxide creates a smooth finish and adds shine and brightness to other colors. 

Most notably, a European Food Safety Authority safety assessment published in May 2021 pointed to genotoxicity concerns, as suggested by previous research. Genotoxicity is the ability of chemicals to damage genetic information such as DNA, which may lead to cancer.