china titanium dioxide uses

In a 2022 study published in the Journal of Hazardous Materials, scientists wanted to examine the effects of titanium dioxide as a food additive on atherosclerosis in mice. (Atherosclerosis refers to a hardening of the arteries.) Researchers fed mice 40 mg/kg of the food additive every day for 4 months, and found that it not only altered gut microbiota but also led to a significantly increased atherosclerotic lesion area, especially in animals that consumed a high-choline western diet (HCD).

...
...

 2) Purification: Add ammonium persulfate to the final immersion solution for one-time oxidation and iron removal, and add activated carbon to adsorb arsenic and iron co-precipitation to achieve the purpose of removing arsenic. Add the polyacrylamide coagulant to separate and filter before separation. The sulfide solution is added to the solution to remove sulfur, and the separated filtrate obtained by the separation is replaced with zinc powder to remove the remaining impurities to obtain a zinc sulfate ammonia complex liquid, which is used in the next step;

...

In a 2020 study published in the Journal of Trace Elements in Medicine and Biology, researchers conducted an in vitro experiment to analyze the effects of TiO2 nanoparticles on a human neuroblastoma (SH-SY5Y) cell line. The scientists evaluated “reactive oxygen species (ROS) generation, apoptosis, cellular antioxidant response, endoplasmic reticulum stress and autophagy.” The results showed that exposure to the nanoparticles “induced ROS generation in a dose dependent manner, with values reaching up to 10 fold those of controls. Nrf2 nuclear localization and autophagy also increased in a dose dependent manner. Apoptosis increased by 4- to 10-fold compared to the control group, depending on the dose employed.” 

...