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In a 2019 study published in the journal Nanotoxicology, researchers recreated the first phase of digestion in mice and fed them titanium dioxide, then examined whether accumulation occurred in the organs. Researchers wrote: “Significant accumulation of titanium was observed in the liver and intestine of E171-fed mice; in the latter a threefold increase in the number of TiO2 particles was also measured. Titanium accumulation in the liver was associated with necroinflammatory foci containing tissue monocytes/macrophages. Three days after the last dose, increased superoxide production and inflammation were observed in the stomach and intestine. Overall, [this] indicates that the risk for human health associated with dietary exposure to E171 needs to be carefully considered.”

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However, challenges remain for China's talc and titanium dioxide industry. Environmental concerns surrounding the mining and processing of these minerals have led to increased scrutiny from both domestic and international regulators. Additionally, competition from other countries with abundant reserves of these minerals could potentially limit China's market share in the future. Despite these challenges, China's role in the global talc and titanium dioxide market is expected to remain significant, as the country continues to invest in its mining infrastructure and explore new applications for these versatile minerals.

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  • >0.7mm
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