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A  2023 study published in the journal Environmental Research, scientists examined the effect of titanium dioxide nanoparticles on important gut bacteria in mice. Their results showed “the growth inhibitory effects could be associated with cell membrane damage caused by titanium dioxide nanoparticles to the bacterial strains. Metabolomics analysis showed that TiO2 NPs caused alterations in multiple metabolic pathways of gut bacteria, such as tryptophan and arginine metabolism, which were demonstrated to play crucial roles in regulating gut and host health.” The researchers also found that four different neuroprotective metabolites “were significantly reduced” in urine and in vitro bacteria and vivo urine samples. The researchers concluded: “Increasing evidence implies that the gut microbiome plays a profound role in regulating host metabolism. Our results illustrated that TiO2 NPs hindered the growth of four beneficial gut bacterial strains.”

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The pricing of lithopone pigments can fluctuate based on several factors, including raw material costs, production processes, and market demand. Typically, wholesale prices reflect the bulk purchasing power, enabling businesses to acquire these materials at a lower cost per unit. Over the years, the market has seen fluctuations in prices due to changes in the supply chain and global economic conditions. It is crucial for buyers to stay informed about these trends to budget effectively and maintain profitability.


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