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  • For a review published in 2023 in the journal Environmental Pollution, researchers examined E171 as a possible factor promoting obesity-related metabolic disorders. Because gut microbiota play an important role in immune function maintenance and development, and because titanium dioxide as a food additive has been shown to alter gut microbiota, researchers wanted to review “the dysregulations along the gut microbiota-immune system axis after oral TiO2 exposure compared to those reported in obese or diabetic patients, and to highlight potential mechanisms by which foodborne TiO2 nanoparticles may increase the susceptibility to develop obesity-related metabolic disorders.” The study authors discovered recurrent changes in the gut microbiota composition when exposed to titanium dioxide nanoparticles, with an imbalance of intestinal symbiotic microbiota. These changes and imbalances were also reported and played a role in the development of obesity, the authors wrote. This highlights “foodborne TiO2 nanoparticles as an endocrine disruptor-like chemical promoting obesity-related disorders,” the authors concluded.

  • Micronized titanium dioxide doesn’t penetrate skin so there’s no need to be concerned about it getting into your body. Even when titanium dioxide nanoparticles are used, the molecular size of the substance used to coat the nanoparticles is large enough to prevent them from penetrating beyond the uppermost layers of skin. This means you’re getting the sun protection titanium dioxide provides with no risk of it causing harm to skin or your body. The coating process improves application, enhances sun protection, and prevents the titanium dioxide from interacting with other ingredients in the presence of sunlight, thus enhancing its stability. It not only makes this ingredient much more pleasant to use for sunscreen, but also improves efficacy and eliminates safety concerns. Common examples of ingredients used to coat titanium dioxide are alumina, dimethicone, silica, and trimethoxy capryl silane.

  • In conclusion, Pretiox is a name synonymous with quality, innovation, and sustainability in the titanium dioxide industry. With a strong commitment to excellence and a passion for continuous improvement, Pretiox has established itself as a leader in the field, trusted by customers around the world. Whether you are looking for high-quality titanium dioxide products for your business or are interested in partnering with a company that prioritizes sustainability, Pretiox is the perfect choice.
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  • When sourcing lithopone for leather production, suppliers must ensure they are purchasing a high-quality product from reputable manufacturers. Consistency in particle size and composition is crucial to achieving the desired color intensity and durability in the final leather goods. By partnering with trusted lithopone suppliers, leather manufacturers can guarantee the quality and performance of their products to meet the expectations of consumers.


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  • Scientists analyzed research that examined how titanium dioxide nanoparticles interact with the brain for a 2015 review published in Nanoscale Research Letters. The researchers wrote: “Once the TiO2 NPs are translocated into the central nervous system through [certain] pathways, they may accumulate in the brain regions. For their slow elimination rates, those NPs could remain in the brain zones for a long period, and the Ti contents would gradually increase with repeated exposure.” After reviewing dozens of studies, the scientists concluded: “Long-term or chronic exposure to TiO2 nanoparticles could potentially lead to the gradually increased Ti contents in the brain, which may eventually induce impairments on the neurons and glial cells and lead to CNS dysfunction as a consequence.”

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  • Anatase and Rutile Key Titanium Dioxide Suppliers in Today's Market
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  • Titanium dioxide, with the chemical formula TiO2 and a specific CAS number 13463-67-7, is an essential raw material pigment widely utilized across various industries due to its exceptional optical properties, high refractive index, and excellent UV resistance. Available in bulk quantities, this 99% pure TiO2 powder serves as a vital ingredient in numerous applications, ensuring superior performance and efficiency.
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  • One of the key players in the titanium dioxide market is wholesale supplier TR 92. TR 92 offers a high-quality titanium dioxide product that meets the stringent requirements of industries such as automotive, construction, and cosmetics. Its superior characteristics make it an ideal choice for applications where color consistency, durability, and performance are critical.
  • Australian researchers examined how titanium dioxide as a food additive affected gut microbiota in mice by orally administering it in drinking water. The study, published in the journal Frontiers in Nutrition in 2019, found the treatment could “alter the release of bacterial metabolites in vivo and affect the spatial distribution of commensal bacteria in vitro by promoting biofilm formation. We also found reduced expression of the colonic mucin 2 gene, a key component of the intestinal mucus layer, and increased expression of the beta defensin gene, indicating that titanium dioxide significantly impacts gut homeostasis.” The changes were then linked to colonic inflammation, along with a higher expression of inflammatory cytokines, which are signal proteins that help with regulation. The researchers concluded that titanium dioxide “impairs gut homeostasis which may in turn prime the host for disease development.”

  • * Adheres to international environmental standards and implements sustainable practices in its operations
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  • Titanium Dioxide for Plastic Factories An Indispensable Additive
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