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Anatase, on the other hand, has an orthorhombic crystal structure and a lower refractive index than rutile. Despite these differences, anatase also possesses excellent photocatalytic properties, making it a promising material for environmental applications such as water treatment and air purification. In addition, anatase's higher surface area and reactivity make it suitable for use in cosmetics, sunscreens, and other personal care products.

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While IARC listed titanium dioxide as “possibly carcinogenic to humans,” they also add that “there is inadequate evidence in humans for the carcinogenicity of titanium dioxide.” Of the four human studies that they reviewed, only one showed a potential risk for occupational workers inhaling titanium dioxide particles and lung cancer, while the other three showed no risk for cancer at all. And it’s key to note that IARC did not assess the effects of titanium dioxide found in foods.

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