While the conclusions of the EU expert panel were considered in this report, Health Canada's Food Directorate conducted its own comprehensive review of the available science. This included evaluating new scientific data that addressed some of the uncertainties identified by the EU expert panel and were not available at the time of their review.    

Is titanium dioxide dangerous? Has it been linked to any health issues?

Lithopone is manufactured by a process (Fig. 1) in which barium sulfide solution is prepared by reducing barite ore (BaSO ₄) with carbon and leaching the resulting mass.