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A study published in the Journal of Agricultural and Food Chemistry in 2019 sought to examine the effects of titanium dioxide on intestinal inflammation. Researchers did this by feeding rats titanium dioxide nanoparticles and found that, after the course of two to three months, the animals had lower body weights and induced intestinal inflammation. The researchers also found the nanoparticles altered gut microbiota composition and aggravated chronic colitis. The rats also experienced reduced populations of CD4+T cells (which are cells that help organize immune responses by prompting other immune cells to fight infection), regulatory T cells, and white blood cells in mesenteric lymph nodes. The researchers wrote: “Dietary TiO2 nanoparticles could interfere with the balance of the immune system and dynamic of gut microbiome, which may result in low-grade intestinal inflammation and aggravated immunological response to external stimulus, thus introducing potential health risk.”

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The global demand for lithopone has been steadily increasing in recent years, driven by the growth of the construction, automotive, and electronics industrieslithopone factory in china. In addition, the increasing awareness of environmental issues has led to a shift towards more sustainable products, which has benefited the lithopone industry. However, the industry also faces challenges such as rising raw material prices and competition from alternative pigments.

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In conclusion, anatase titanium dioxide is a safe and effective food-grade additive that provides a range of functional benefits to food products. Its stability, inertness, and lack of adverse effects make it an ideal choice for use in a wide variety of food applications. While there are still some unanswered questions about the safety of TiO2, the available evidence suggests that it is safe for use in food products at current levels of consumption.

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