In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2. With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”
By incorporating titanium dioxide into dyes, manufacturers can achieve a wider range of colors and shades, as well as ensure that the colors remain bright and fade-resistant even after repeated washing or exposure to sunlight By incorporating titanium dioxide into dyes, manufacturers can achieve a wider range of colors and shades, as well as ensure that the colors remain bright and fade-resistant even after repeated washing or exposure to sunlightplastic and dyeing used titanium dioxide r218 factory. R218 factory produces titanium dioxide that is specifically designed for use in dyes, allowing textile manufacturers to create high-quality, colorfast materials for a variety of applications.