tio2 used in rubber factory

Titanium Dioxide (TiO2), a widely used compound across various industries due to its exceptional refractive index and high photocatalytic activity, is an essential component in sectors ranging from cosmetics to paints and coatings, food additives, and even solar panels. The wholesale TiO2 market plays a crucial role in ensuring a steady supply of this versatile material; however, with its extensive usage comes the responsibility of maintaining stringent safety measures.

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In vitro, in the hemocytes of the marine mussel Mytilus hemocytes, suspension of TiO2 NPs (Degussa P25, 10 μg/ml) stimulated immune and inflammatory responses, such as lysozyme release, oxidative burst and nitric oxide production. Vevers and Jha demonstrated the intrinsic genotoxic and cytotoxic potential of TiO2 NPs on a fish-cell line derived from rainbow-trout gonadal tissue (RTG-2 cells) after 24 h of exposure to 50 μg/ml. Reeves et al. demonstrated a significant increase in the level of oxidative DNA damage in goldfish cells, and suggested that damage could not repaired by DNA repair mechanisms. Another suggestion from the mentioned study was that hydroxyl radicals are generated also in the absence of UV light. It has been shown that fish cells are generally more susceptible to toxic/oxidative injury than mammalian cells.

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