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The National Cancer Institute tested TiO₂ for possible carcinogenicity by the oral route of exposure by feeding rats and mice with TiO₂ (size not specified) at doses 25,000 or 50,000 ppm TiO₂ for 103 weeks. They concluded that TiO₂ was not carcinogenic.Also, the study with rats fed diets containing up to 5 % TiO₂ coated mica for 130 weeks showed no treatment-related carcinogenicity. Since the size and other TiO₂ properties were not specified or determined, we cannot generalize this conclusion and we have to take into account other possible outcomes of this scenario in different exposure conditions (other size/crystalline structure of TiO₂ etc.).

Package:
25KG/50KG Woven bag with inner, or 1000kg big woven plastic bag.



Company Information
     Loman Chemical Group (include Shanghai Loman Chemical Co Ltd; Wuhu Loman Chemical Co Ltd and Wuhu Loman Titanium Industial Co Ltd.)is one of the main titanium dioxide manufacturers in china, producing various high quality Anatase and Rutile titanium dioxide. Loman brand products, has being widely used in paper, paint, plastic, ink, coating, rubber, cosmetic, food, fiber, etc.
      In order to meet different requirements of various customers, we actively expand producing other pigments, include Lithopone, Barium sulfate and Silica. Annual production volume of anatase and rutile grade titanium dioxide have reached 100,000 tons, lithopone 30.000 tons, barium sulfate 50.000 tons and precipitated silica 8.000 tons. The Loman brand is one of the famous brands in China, having great popularity both at home and abroad. Our products have been widely used in European, North America and Southeast Asia. 

Our advantages:
1)With the most professional manufacturers,High quality and high safety product

2)Professional consulting services are availabe for you at antyime

3)Have a favorable price ,reliable quality

4)Complete products meet your purchasing need

A study published in the Journal of Agricultural and Food Chemistry in 2019 sought to examine the effects of titanium dioxide on intestinal inflammation. Researchers did this by feeding rats titanium dioxide nanoparticles and found that, after the course of two to three months, the animals had lower body weights and induced intestinal inflammation. The researchers also found the nanoparticles altered gut microbiota composition and aggravated chronic colitis. The rats also experienced reduced populations of CD4+T cells (which are cells that help organize immune responses by prompting other immune cells to fight infection), regulatory T cells, and white blood cells in mesenteric lymph nodes. The researchers wrote: “Dietary TiO2 nanoparticles could interfere with the balance of the immune system and dynamic of gut microbiome, which may result in low-grade intestinal inflammation and aggravated immunological response to external stimulus, thus introducing potential health risk.”