titanium dioxide used in medicine

...

Lithopone, a staple in the paint industry, boasts a unique blend of properties that make it an indispensable component for achieving high-quality finishes. Among its many variants, B301 and B311 stand out as two of the most sought-after types due to their specific characteristics and performance metrics. In this brief exploration, we will delve into the significance of these lithopone grades, discuss factors affecting their price lists, and highlight the role of reputable suppliers in ensuring consistent quality and availability.

...

Drobne et al. used the terrestrial arthropod Porcellio scaber as a test organism for determining the cytotoxic effect of TiO2 NPs (anatase). The animals were exposed to TiO2 NPs of two different sizes (25 nm and 75 nm) in the concentration range 10–1000 μg TiO2/g dry food for 3 to 14 days. No adverse effects, such as mortality, body weight changes or reduced feeding, were observed. In fact, quite the opposite, an enhanced feeding rate, food absorption efficiency and increase in catalase activity were observed. The intensity of these responses appeared to be time- but not dose-dependent. It should also be noted that the concentrations tested in this study were much higher than the predicted concentration (4.8 μg/g soil) at high emission scenario of nano-sized TiO2. Using the same test organism another group showed that exposure to TiO2 NPs induced destabilization of cell membrane in the epithelium of digestive glands isolated from exposed animals. They also showed that this effect can be observed after just 30 minutes of exposure.

...