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Mexican researchers sought to evaluate the effects of E171 across a span of conditions in mice, including its influence on behavior, along with the effects on the colon and liver. The research, published in 2020 in the journal Food and Chemical Toxicology, showed that E171 promoted anxiety and induced adenomas, or noncancerous tumors, in the colon. They also found that E171 heightened goblet cells hypertrophy and hyperplasia, which is typically seen in asthma patients and triggered by smoking or external pollutants and toxins. They also noted mucins overexpression in the mice, which can be linked to cancer cell formation. 

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Sachtleben's journey into the world of TiO2 production began with a clear vision to manufacture high-performance pigments that not only meet but exceed industry standards. Their commitment to excellence is evident in the rigorous processes employed at their state-of-the-art facilities. Using cutting-edge technology, they have refined the traditional chloride process for producing TiO2, ensuring unparalleled purity and consistent color strength in their products.

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