titanium dioxide toothpaste manufacturers

All samples (n = 6) were irradiated in a 96 well plate using an LED panel on top for 3 and 6 h before analysis. An identical set of samples were kept in the dark as controls. The temperature was checked and did not go over 37 °C. The intensity of light was also measured and was constant at 19,500.10 lux. (43.33 W in 0.2 m2), about 5 times less than actual solar light intensity on Earth's surface Therefore, these findings are indicative of even greater danger in real life.

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titanium dioxide toothpaste manufacturers2025-08-14 17:14
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titanium dioxide toothpaste manufacturers2025-08-14 16:26
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We've used titanium dioxide safely for decades. However, recently its safety was called into question. 
 
At CRIS, we've explored the safety of titanium dioxide for nearly half a decade, including conducting double-blind research to test the safety of food-grade titanium dioxide (E171). Our study shows that when exposed to food-grade titanium dioxide in normal conditions, research animals did not experience adverse health outcomes.
 
It's important to emphasize that in a National Institutes of Health study, experimental animals were exposed to titanium dioxide in amounts as high as 5% of their diet for a lifetime and showed no evidence of adverse effects. 
 
A handful of studies greatly influenced the decisions made by the European Food Safety Authority (EFSA). Unfortunately, these studies did not consider that titanium dioxide exposure comes from food, not drinking water. Additionally, CRIS researchers could not reproduce the adverse outcomes identified by the studies through typical food ingestion. Regardless, the EFSA banned E171 as a food ingredient and for use in other capacities in the summer of 2022.
 
In 2022, the United States, United Kingdom, and Canada maintained that the scientific evidence supports that titanium dioxide (E171) is safe for humans to use and consume.

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titanium dioxide toothpaste manufacturers2025-08-14 15:59
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A few non-dietary studies have reported adverse effects in the gastrointestinal tract of laboratory animals given food-grade TiO2. However, these same effects were not seen when the same or higher doses of food-grade TiO2 were administered in the animals' diet. Dietary studies best reflect how humans are exposed to TiO2 from food. Thus, the Food Directorate placed the most emphasis on the results of these studies in the state of the science report.

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titanium dioxide toothpaste manufacturers2025-08-14 15:18
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