A 2023 study published in the journal Particle and Fibre Toxicology set out to examine the impact of titanium dioxide nanoparticles in mice “on the course and prognosis of ulcerative colitis,” by creating an ulcerative colitis disease model. Researchers found that the titanium dioxide nanoparticles significantly increased the severity of colitis. They also “decreased the body weight, increased the disease activity index and colonic mucosa damage index scores, shortened the colonic length, increased the inflammatory infiltration in the colon.” Researchers concluded: “Oral intake of TiO2 nanoparticles could affect the course of acute colitis in exacerbating the development of ulcerative colitis, prolonging the ulcerative colitis course and inhibiting ulcerative colitis recovery.”

Plus, titanium dioxide is chemically inert, meaning it won't react with other substances in the paint. This stability ensures that the paint retains its original color and properties over time, preventing discolouration and degradation. Using titanium dioxide as an ingredient, the paint can withstand harsh weather conditions and prevent flaking, peeling or chalking. This exceptional durability makes it ideal for interior and exterior walls, ensuring a long-lasting and beautiful finish.

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In 2021, the European Food Safety Authority concluded that titanium dioxide is no longer safe in foods due to the same concerns over nanoparticles. As a result, titanium dioxide is now banned as a food additive in the EU. Although studies have shown that the absorption of ingested titanium dioxide is low, evidence suggests that titanium dioxide nanoparticles can accumulate in the body over time. Health Canada deemed it safe in 2022 but noted concerns. Unlike their European counterparts, Canadian officials did not consider studies performed with titanium dioxide nanoparticles alone. 

Le lithopone a été découvert dans les années 1870 par DuPont. Il a été produit par la Krebs Pigments and Chemical Company, entre autres¹. Il se faisait en différents grades, en fonction de la teneur en sulfure de zinc. Les qualités « bronze » et « or » contenaient 40 à 50 % de sulfure de zinc, ce qui les rendaient particulièrement couvrantes². Bien que ce pigment ait atteint son pic de popularité autour de 1920, il s'en produisait encore annuellement plus de 220 000 tonnes en 1990. Il est principalement utilisé dans les peintures, les pâtes et les plastiques³.

Hebei Caixin Material Technology Co., LTD., formerly established in 2005, is located in the core of Beijing-Tianjin-Hebei City cluster, close to Tianjin Port, the largest port in the north, with developed transportation and outstanding people. After the continuous efforts of Caiqing people, has accumulated assets for the company of nearly 200 million, nearly 1,000 employees, Caiqing technology has become the pigment titanium dioxide research and development, production, sales and import and export trade in one of the large company, we integrate industry resources, to provide personalized customized services for global customers. We adhere to the market-oriented, good faith as the principle, is committed to open up a diversified international market, for the world customers to provide quality products, efficient service, is our unremitting pursuit. We sincerely invite customers from all over the world to visit our company.

④ Ink industry: titanium dioxide is also an indispensable white pigment in advanced ink. The ink containing titanium dioxide is durable and does not change color, has good surface wettability and is easy to disperse. The titanium dioxide used in the ink industry includes rutile and anatase.

Skin-penetration studies