lithopone 28 b301 30 b311
no changes to DNA in various animal studies
Reasons for listing: Henan Billions Chemical Co., Ltd., a well-known brand of TiO2 factory, a famous trademark in Henan Province, a listed company, a drafting unit of national and industry standards, a high-tech enterprise, advocating the implementation of clean production, focusing on titanium and zirconium fine powder A large-scale inorganic fine chemical enterprise engaged in material R&D and manufacturing.
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2025-08-15 06:38
1787
At the present JECFA meeting, the committee considered additional toxicological studies relevant to the safety assessment of the chemical that investigated its toxicokinetics, acute toxicity, short-term toxicity, long-term toxicity and carcinogenicity, genotoxicity, and reproductive and developmental toxicity, as well as special studies addressing its short-term initiation/promotion potential for colon cancer. The experts acknowledged that a large number of toxicological studies have been conducted using test materials, including nanoparticles, having size distributions and physico-chemical properties not comparable to real-world uses of titanium dioxide as a food additive. The studies on non-representative materials were evaluated by JECFA, but the committee concluded that such studies are not relevant to the safety assessment of the additive.
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2025-08-15 05:59
795
Because of their small size, nanoparticles may have unique physical and chemical properties. These properties may cause them to interact with living systems differently than larger materials with the same chemical composition (also known as bulk materials).
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2025-08-15 05:00
111
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2025-08-15 05:00
2039
Acknowledgments
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2025-08-15 04:39
1077
Anatase Titanium Dioxide, commonly known as food-grade titanium dioxide, is a versatile and widely used substance in the food industry. This compound is recognized for its exceptional properties, including its bright white color, high refractive index, and excellent stability. Due to these characteristics, it has become an essential ingredient in various food products, playing a crucial role in enhancing their appearance and shelf life.
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2025-08-15 04:28
1305
At the present JECFA meeting, the committee considered additional toxicological studies relevant to the safety assessment of the chemical that investigated its toxicokinetics, acute toxicity, short-term toxicity, long-term toxicity and carcinogenicity, genotoxicity, and reproductive and developmental toxicity, as well as special studies addressing its short-term initiation/promotion potential for colon cancer. The experts acknowledged that a large number of toxicological studies have been conducted using test materials, including nanoparticles, having size distributions and physico-chemical properties not comparable to real-world uses of titanium dioxide as a food additive. The studies on non-representative materials were evaluated by JECFA, but the committee concluded that such studies are not relevant to the safety assessment of the additive.
Because of their small size, nanoparticles may have unique physical and chemical properties. These properties may cause them to interact with living systems differently than larger materials with the same chemical composition (also known as bulk materials).
Acknowledgments
Anatase Titanium Dioxide, commonly known as food-grade titanium dioxide, is a versatile and widely used substance in the food industry. This compound is recognized for its exceptional properties, including its bright white color, high refractive index, and excellent stability. Due to these characteristics, it has become an essential ingredient in various food products, playing a crucial role in enhancing their appearance and shelf life.
This precipitate is not suitable for a pigment until it is filtered, dried, crushed, heated to a high temperature and quenched in cold water. The second heating in a muffle furnace at 725 °C produces crystals of the right optical size.