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Scientists analyzed research that examined how titanium dioxide nanoparticles interact with the brain for a 2015 review published in Nanoscale Research Letters. The researchers wrote: “Once the TiO2 NPs are translocated into the central nervous system through [certain] pathways, they may accumulate in the brain regions. For their slow elimination rates, those NPs could remain in the brain zones for a long period, and the Ti contents would gradually increase with repeated exposure.” After reviewing dozens of studies, the scientists concluded: “Long-term or chronic exposure to TiO2 nanoparticles could potentially lead to the gradually increased Ti contents in the brain, which may eventually induce impairments on the neurons and glial cells and lead to CNS dysfunction as a consequence.”

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In conclusion, TiO2 is a valuable and essential component in the paper industry. Paper suppliers rely on TiO2 to improve the brightness, opacity, color, and durability of their products, ensuring that they meet the highest standards of quality and performance. With its excellent light-scattering properties, high refractive index, UV-blocking abilities, and environmentally friendly characteristics, TiO2 is a versatile pigment that is driving innovation and excellence in the paper manufacturing process. As the demand for high-quality paper products continues to grow, TiO2 will remain a key ingredient in the success of paper suppliers worldwide.

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