The process of creating crushed red pepper begins with sorting and cleaning the peppers to remove any impurities. The peppers are then dried using a variety of methods, including sun drying or mechanical drying, to reduce their moisture content. Once dried, the peppers are ground into flakes or powder using specialized equipment in the factory.

In order to generate this chain of chemical reactions, signaling molecules are produced and released by the cell, leading to more inflammatory responses and a continuous cycle of cells and molecules, meaning that the inflammatory response becomes more severe. Many studies have shown that curcumin blocks these cellular signals, thus helping to maintain the number of inflammatory response proteins and cells. However, in many of these studies, researchers have found that curcumin has poor bioavailability.