In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

Lomon, one of the leading titanium dioxide manufacturers in China, produces the R996 grade titanium dioxide with purity levels exceeding 99%. This high purity ensures that the pigment provides excellent hiding power and color retention in paints, making it a popular choice for the paint industry.

Colour Characteristics

lithopone supplier 30% is the perfect solution for partial substitution of TiO2 in fillers due to its very soft nature and hardly any shrinkage properties.