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The pigment lithopone industry has undergone a significant transformation over the past century, with factories playing a crucial role in the production and distribution of this essential compound. Lithopone, a vital component in various industries such as paints, plastics, and printing inks, is a fine white powder consisting of a mixture of zinc sulfide and barium sulfate. This article will explore the evolution of pigment lithopone factories, their impact on the global market, and future prospects.

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Mexican researchers sought to evaluate the effects of E171 across a span of conditions in mice, including its influence on behavior, along with the effects on the colon and liver. The research, published in 2020 in the journal Food and Chemical Toxicology, showed that E171 promoted anxiety and induced adenomas, or noncancerous tumors, in the colon. They also found that E171 heightened goblet cells hypertrophy and hyperplasia, which is typically seen in asthma patients and triggered by smoking or external pollutants and toxins. They also noted mucins overexpression in the mice, which can be linked to cancer cell formation. 

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