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For research published in 2022 study in the journal Food and Chemical Toxicology, scientists examined “the genotoxicity and the intracellular reactive oxygen species induction by physiologically relevant concentrations of three different TiO2 nanomaterials in Caco-2 and HT29-MTX-E12 intestinal cells, while considering the potential influence of the digestion process in the NMs’ physiochemical characteristics.” They found a “DNA-damaging effect dependent on the nanomaterial,” along with the micronucleus assay suggesting “effects on chromosomal integrity, an indicator of cancer risk, in the HT29-MTX-E12 cells, for all the tested TiO2 nanomaterials.” Researchers concluded that the results showcase “evidence of concern” regarding titanium dioxide used as a food additive.

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The global lithopone market has seen a steady growth over the years, driven by the increasing demand from end-use industries, particularly construction and coatings. However, the market faces challenges, including price volatility due to raw material fluctuations and the ongoing shift towards more eco-friendly alternatives. This has led suppliers to invest in research and development to improve the sustainability of their products and processes.

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In conclusion, Ponceau 4R and titanium dioxide are two valuable ingredients in the cosmetics industry, offering versatility, stability, effectiveness, and safety. By understanding their properties and benefits, manufacturers can make informed decisions when formulating their products. With proper sourcing and handling, these ingredients can help create high-quality cosmetic products that meet the needs and expectations of consumers.

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  • Challenges and Considerations


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