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Prof. Maged Younes, Chair of EFSA’s expert Panel on Food Additives and Flavourings (FAF), wrote of the decision: “Taking into account all available scientific studies and data, the Panel concluded that titanium dioxide can no longer be considered safe as a food additive. A critical element in reaching this conclusion is that we could not exclude genotoxicity concerns after consumption of titanium dioxide particles. After oral ingestion, the absorption of titanium dioxide particles is low, however they can accumulate in the body.”

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The vitaminB2@TiO2NPs were obtained at room temperature, by a method developed after trying several ratios of reactants. Briefly, 0.02 g of P25TiO2NPs were dispersed in 1 mL of ultra-pure water and stirred in a Vortex. Next, 200 μl of vitamin B2 dissolved in ultra-pure water (5.3 × 10−3 M) were added to 200 μL of P25TiO2NPs and the mixture was ultrasonicated for 1 hour to achieve a deep-yellow homogeneous suspension. The pellet obtained after centrifuging the suspension for 10 min at 4500 rpm was resuspended in ultrapure water, centrifuged again, and then lyophilized.

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In conclusion, while both lithopone and titanium dioxide have their advantages and disadvantages, TiO2 appears to be the better choice for most applications. Its superior whiteness, UV protection properties, and chemical stability make it a popular choice in the paint, plastics, and paper industries. However, for applications where cost and safety are primary concerns, lithopone may still be a viable option. Ultimately, the choice between these two pigments will depend on the specific requirements of the application and the desired balance of performance and cost.

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Modern lithopone factories are at the forefront of this revolution. They employ cutting-edge technology to reduce energy consumption and optimize production processes. Advanced filtration systems ensure that the end product is free from impurities, while closed-loop systems recycle water and other byproducts, significantly reducing the environmental footprint. Moreover, these facilities are increasingly powered by renewable energy sources, aligning manufacturing practices with sustainability goals.

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