Although the evidence for general toxic effects was not conclusive, on the basis of the new data and strengthened methods our scientists could not rule out a concern for genotoxicity and consequently they could not establish a safe level for daily intake of TiO₂ as a food additive.

Titanium dioxide holds exceptional significance as a white pigment due to its superior scattering capabilities, remarkable chemical stability, and non-toxic nature. Among all white pigments, it surpasses others in terms of its ability to scatter light effectively. Consequently, titanium dioxide stands as the most significant inorganic pigment, accounting for the highest quantity in usage. The majority part of the global production of ilmenite and rutile is dedicated to the production of TiO2 pigments. The remaining portion is utilized for the manufacturing of titanium metal and in the production of welding electrodes.