titanium dioxide uses manufacturer

In a 2016 study published in Scientifica (Cairo), Egyptian researchers examined the effects of titanium dioxide nanoparticles on the organs of mice by orally administering the food additive daily, for five days. The results showed that the exposure produced “mild to moderate changes in the cytoarchitecture of brain tissue in a time dependent manner.” Furthermore, “Comet assay revealed the apoptotic DNA fragmentation, while PCR-SSCP pattern and direct sequencing showed point mutation of Presenilin 1 gene at exon 5, gene linked to inherited forms of Alzheimer’s disease.” The researchers wrote: “From these findings, “the present study concluded that TiO2NPs is genotoxic and mutagenic to brain tissue which in turn might lead to Alzheimer’s disease incidence.”

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Modern production facilities employ state-of-the-art technologies to ensure particle size distribution is optimal, which is crucial for the pigment's performance in end-use applications. Advanced filtration systems remove impurities, ensuring that the final product meets the highest purity levels. Additionally, manufacturers pay close attention to environmental concerns by implementing waste management strategies to minimize any negative impact during the production process.

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