tio2 white pigment manufacturers

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Another key player in the Chinese titanium dioxide industry is CNNC Hua Yuan Titanium Dioxide Co., Ltd. The company was founded in 1958 and is a subsidiary of China National Nuclear Corporation (CNNC). CNNC Hua Yuan Titanium Dioxide is known for its state-of-the-art production facilities and dedication to research and development. The company's products are widely used in coatings, plastics, and other industries, making it a highly influential manufacturer in the global titanium dioxide market
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china titanium dioxide manufacturers.

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In a study published in the journal Environmental Toxicology and Pharmacology in 2020, researchers examined the effects of food additives titanium dioxide and silica on the intestinal tract by grouping and feeding mice three different food-grade particles — micro-TiO2, nano-TiO2, and nano-SiO2.  With all three groups, researchers observed changes in the gut microbiota, particularly mucus-associated bacteria. Furthermore, all three groups experienced inflammatory damage to the intestine, but the nano-TiO2 displayed the most pronounced changes. The researchers wrote: “Our results suggest that the toxic effects on the intestine were due to reduced intestinal mucus barrier function and an increase in metabolite lipopolysaccharides which activated the expression of inflammatory factors downstream. In mice exposed to nano-TiO2, the intestinal PKC/TLR4/NF-κB signaling pathway was activated. These findings will raise awareness of toxicities associated with the use of food-grade TiO2 and SiO2.”

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