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Les pouvoirs couvrant et éclaircissant du lithopone normal sont supérieurs à ceux de la céruse et de l'oxyde de zinc, mais inférieurs au Dioxyde de Titane pur, étant le meilleur blanc sous tout rapport. C'est le sulfure de zinc qui, avec son indice de réfraction de 2,37, est l’élément opaque ; le 2nd composé, le sulfate de baryum, joue un rôle de diluant minéral et favorise l'efficacité de la diffusion du premier.
5. Regulatory compliance The MSDS should also include information on regulatory requirements for the safe handling and use of lithopone, including any permits or certifications that may be necessary.
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In a study published in the journal Toxicology, researchers examined the effects of exposing human colon cancer cell line (HTC116) titanium dioxide food additives in vitro. “In the absence of cytotoxicity, E171 was accumulated in the cells after 24 hours of exposure, increasing granularity and reactive oxygen species, inducing alterations in the molecular pattern of nucleic acids and lipids, and causing nuclei enlargement, DNA damage and tubulin depolymerization,” the scientists wrote. Researchers removed the additive from the culture, then examined the results 48 hours later. They found, “The removal of E171 was unable to revert the alterations found after 24 h of exposure in colon cells. In conclusion, exposure to E171 causes alterations that cannot be reverted after 48 h if E171 is removed from colon cells.”