china titanium dioxide in coatings

Additionally, the committee noted that the available data did not provide convincing evidence of genotoxicity for titanium dioxide as a food additive, but recognized the limitations in current methodologies with respect to the testing of poorly soluble particulate materials. Although there were uncertainties in the genotoxicity data, the experts took into account the fact that the additive was not carcinogenic in adequately conducted two-year studies in mice and rats at doses of up to 7,500 mg/kg BW per day for mice, and 2,500 mg/kg BW per day for rats, the highest doses tested. There was also no evidence of reproductive or developmental toxicity in studies in rats at doses up to 1,000 mg/kg BW per day, the highest doses tested.  

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Titanium dioxide, a white inorganic compound widely used as a pigment in paints, plastics, paper, and other products, is an essential material in the modern industrial world. Its unique properties, such as high refractive index and strong brightness, make it an ideal substance for various applications. However, like many commodities, the price of titanium dioxide is subject to fluctuations influenced by several factors including supply and demand dynamics, production costs, and geopolitical events.

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