Increased severity of ulcerative colitis
...
2025-08-15 04:40
1930
pretiox titanium dioxide
Both P25TiO2NPs (with or without vitamin B2) were not found beyond the epidermis in 99% of the analyzed TEM images (Fig. 8). This is coherent with previous findings showing that nanoparticles greater than 50 nm can not penetrate the skin, even in vivo models with movement, stretching, and friction [54]. However, in one of the zones, a few nanoparticles were observed inside a hair follicle. This could be due to the follicle exposure after the localized rupture of this physical barrier when rats were shaved in order to clean the area for cream topical administration. This finding suggests that nanoparticle-based sunscreen should not be applied on recently shaved or harmed skin, in order to avoid nanoparticle skin penetration.
...
2025-08-15 04:31
721
Manufacturers of products with titanium dioxide play a critical role in the industry by ensuring that their products meet the highest quality and safety standards. These manufacturers must adhere to strict guidelines set forth by regulatory agencies to ensure that their products are safe for consumer use. Additionally, manufacturers must also invest in research and development to continually improve their products and stay ahead of the competition.
...
2025-08-15 04:24
939
...
2025-08-15 03:58
237
ROS
...
2025-08-15 03:38
2821
In recent decades, concerns for the risks of titanium dioxide consumption have grown.
...
2025-08-15 03:33
369
In May 2021, the European Food Safety Authority (EFSA) published an opinion that stated that titanium dioxide can no longer be considered safe when used as a food additive.
...
2025-08-15 03:12
2217
...
2025-08-15 02:58
1125
Duan et al. administered 125 mg/kg BW or 250 mg/kg BW of anatase TiO2 (5 nm) intragastrically to mice continuously for 30 days. The exposed mice lost body weight, whereas the relative liver, kidney, spleen and thymus weights increased. Particles seriously affected the haemostasis of the blood and the immune system. The decrease in the immune response could be the result of damage to the spleen, which is the largest immune organ in animals and plays an important role in the immune response. Powel et al. demonstrated that TiO2 NPs may trigger immune reactions of the intestine after oral intake. They showed that TiO2 NPs conjugated with bacterial lipopolysaccharide, but not TiO2 NPs or lipopolysaccharide alone, trigger the immune response in human peripheral blood mononuclear cells and in isolated intestinal tissue. This indicates that TiO2 NPs may be important mediators in overcoming normal gut-cell hyporesponsiveness to endogenous luminal molecules, which may be particularly relevant to patients with inflammatory bowel disease, which is characterized by an abnormal intestinal permeability.
...
2025-08-15 02:48
2933
Manufacturers have responded by exploring alternatives, such as natural colorants, though these often cannot match the vibrant whiteness provided by TiO2. The shift towards more natural ingredients aligns with growing consumer preferences for transparency and minimal processing in their food.
...
2025-08-15 02:45
785
...
2025-08-15 03:38
2821
In recent decades, concerns for the risks of titanium dioxide consumption have grown.
...
2025-08-15 03:33
369
In May 2021, the European Food Safety Authority (EFSA) published an opinion that stated that titanium dioxide can no longer be considered safe when used as a food additive.
...
2025-08-15 03:12
2217
...
2025-08-15 02:58
1125
Duan et al. administered 125 mg/kg BW or 250 mg/kg BW of anatase TiO2 (5 nm) intragastrically to mice continuously for 30 days. The exposed mice lost body weight, whereas the relative liver, kidney, spleen and thymus weights increased. Particles seriously affected the haemostasis of the blood and the immune system. The decrease in the immune response could be the result of damage to the spleen, which is the largest immune organ in animals and plays an important role in the immune response. Powel et al. demonstrated that TiO2 NPs may trigger immune reactions of the intestine after oral intake. They showed that TiO2 NPs conjugated with bacterial lipopolysaccharide, but not TiO2 NPs or lipopolysaccharide alone, trigger the immune response in human peripheral blood mononuclear cells and in isolated intestinal tissue. This indicates that TiO2 NPs may be important mediators in overcoming normal gut-cell hyporesponsiveness to endogenous luminal molecules, which may be particularly relevant to patients with inflammatory bowel disease, which is characterized by an abnormal intestinal permeability.
...
2025-08-15 02:48
2933
Manufacturers have responded by exploring alternatives, such as natural colorants, though these often cannot match the vibrant whiteness provided by TiO2. The shift towards more natural ingredients aligns with growing consumer preferences for transparency and minimal processing in their food.
...
2025-08-15 02:45
785
≥99.0
This duality makes it a popular choice for both rural and urban landscapes, as it can seamlessly blend into both settings This duality makes it a popular choice for both rural and urban landscapes, as it can seamlessly blend into both settings