The pricing of lithopone pigments can fluctuate based on several factors, including raw material costs, production processes, and market demand. Typically, wholesale prices reflect the bulk purchasing power, enabling businesses to acquire these materials at a lower cost per unit. Over the years, the market has seen fluctuations in prices due to changes in the supply chain and global economic conditions. It is crucial for buyers to stay informed about these trends to budget effectively and maintain profitability.

Lithopone in plastics and masterbatch

TiO₂ NPs appeared to be more toxic to nematode Caenorhabditis elegans than submicron-sized TiO_2.  At a concentration of 1 mg/l, 7 nm particles affected its fertility and survival rate and were more toxic than 20 nm anatase particles. Similarly, Hu et al. showed that rutile particles (10–20 nm), at concentrations above 1 g/kg soil, can be bio-accumulated in earthworms, where they induce oxidative stress, inhibit the activity of cellulase and induce DNA and mitochondrial damage.