tio2 used in rubber factory

The primary function of Anatase Titanium Dioxide in food is as a coloring agent. Its intense whiteness can effectively brighten and whiten foods such as powdered sugar, confectionery, and dairy products. By adding small amounts of this compound, manufacturers can achieve a more visually appealing product that attracts consumers. Moreover, its high refractive index means that it can be used to add a glossy finish to certain foods, further enhancing their appeal.

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Another critical advantage of using TiO2 in pigments is its non-toxic nature. Unlike some traditional pigments that may contain heavy metals or other harmful substances, TiO2 is recognized as safe by regulatory bodies around the world. This attribute allows manufacturers to develop products that are not only visually appealing but also meet stringent health and safety requirements. As consumer awareness about health issues increases, the demand for non-toxic pigments continues to rise, further solidifying TiO2's position in the market.

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Duan et al. administered 125 mg/kg BW or 250 mg/kg BW of anatase TiO2 (5 nm) intragastrically to mice continuously for 30 days. The exposed mice lost body weight, whereas the relative liver, kidney, spleen and thymus weights increased. Particles seriously affected the haemostasis of the blood and the immune system. The decrease in the immune response could be the result of damage to the spleen, which is the largest immune organ in animals and plays an important role in the immune response. Powel et al. demonstrated that TiO2 NPs may trigger immune reactions of the intestine after oral intake. They showed that TiO2 NPs conjugated with bacterial lipopolysaccharide, but not TiO2 NPs or lipopolysaccharide alone, trigger the immune response in human peripheral blood mononuclear cells and in isolated intestinal tissue. This indicates that TiO2 NPs may be important mediators in overcoming normal gut-cell hyporesponsiveness to endogenous luminal molecules, which may be particularly relevant to patients with inflammatory bowel disease, which is characterized by an abnormal intestinal permeability.

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