Animal studies have shown that, when consumed as a food additive, titanium dioxide can induce intestinal inflammation.

In 2023, California and New York proposed banning several food additives that are banned in Europe but legal in the United States. Titanium dioxide was among the five proposed to be banned, but in September, the additive was removed from the list of additives from the California ban list.

Fig. 1. Weight loss (%) of vitaminB2@P25TiO₂NPs.

Lithopone 30% CAS No. 1345-05-7 / Storage method