medical use of barium sulfate

While this ruling from the EU General Court doesn’t immediately change the regulations surrounding titanium dioxide, nor does it change the ban that went into place in 2022, it does put the ingredient back in the spotlight.
 
In the coming months, we will see how the ruling impacts the regulations around titanium dioxide (E171), and we’ll see if the European Food Safety Authority (EFSA) will take another look at the body of scientific evidence used to justify the current ban on E171 in foods and pharmaceuticals.

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  • TiO2 NPs appeared to be more toxic to nematode Caenorhabditis elegans than submicron-sized TiO2.  At a concentration of 1 mg/l, 7 nm particles affected its fertility and survival rate and were more toxic than 20 nm anatase particles. Similarly, Hu et al. showed that rutile particles (10–20 nm), at concentrations above 1 g/kg soil, can be bio-accumulated in earthworms, where they induce oxidative stress, inhibit the activity of cellulase and induce DNA and mitochondrial damage.

  • However, the run rates improved after the Chinese government's consistent efforts to reduce electricity rationing in China. The demand forecast remained positive during the quarter, with inquiries coming in from both the local and international markets. As a result of the supply-demand mismatch, the FOB Wuhu debate for TiO2 rutile grade was decided at 3097 USD/MT at the end of the quarter.